Esophageal Issues such as noncardiac upper body discomfort, swallowing disorders, and regurgitation/rumination syndromes are popular in clinical practice. Virtually all gastroenterologists and physicians managing these Diseases offer empiric and symptomatic treatment method without the need of an evaluation or knowledge of the cause of the signs. In a review In https://www.directivepublications.org/journal-of-gastroenterology-hepatology-and-endoscopy-research/