The principal cytochrome P450 isoenzyme involved appears for being CYP2E1, with CYP1A2 and CYP3A4 as supplemental pathways. Roughly eighty five% of the oral dose seems during the urine within 24 hours of administration, most given that the glucuronide conjugate, with small amounts of other conjugates and unchanged drug. Acetaminophen and https://britedirectory.com/listings13181804/promethazine-with-codeine-doses-for-adults-an-overview